A Pertovaara Selected Research

radolmidine

1/2002	The influence of chemical sympathectomy on pain responsivity and alpha 2-adrenergic antinociception in neuropathic animals.
10/2000	Selective and segmentally restricted antinociception induced by MPV-2426, a novel alpha-2-adrenoceptor agonist, following intrathecal administration in the rat.
7/2000	The dissociation of sedative from spinal antinociceptive effects following administration of a novel alpha-2-adrenoceptor agonist, MPV-2426, in the locus coeruleus in the rat.
6/2000	The mechanical antihyperalgesic effect of intrathecally administered MPV-2426, a novel alpha2 -adrenoceptor agonist, in a rat model of postoperative pain.

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A Pertovaara Research Topics

Disease

16	Pain (Aches) 12/2019 - 04/2000
7	Hypersensitivity (Allergy) 08/2016 - 01/2001
4	Neuralgia (Stump Neuralgia) 10/2017 - 09/2013
4	Hyperalgesia 05/2014 - 06/2000
3	Inflammation (Inflammations) 12/2010 - 03/2001
2	Diabetes Mellitus 12/2019 - 08/2016
2	Diabetic Neuropathies (Diabetic Neuropathy) 12/2019 - 02/2001
1	Mood Disorders (Mood Disorder) 05/2014
1	Chronic Pain 05/2014
1	Anhedonia 05/2014
1	Obesity 07/2012
1	Parkinson Disease (Parkinson's Disease) 12/2010
1	Alzheimer Disease (Alzheimer's Disease) 06/2010
1	Neurobehavioral Manifestations 06/2010
1	Acute Pain 01/2002
1	Wounds and Injuries (Trauma) 06/2000
1	Postoperative Pain 06/2000

Drug/Important Bio-Agent (IBA)

4	radolmidineIBA 01/2002 - 06/2000
3	Opioid Analgesics (Opioids)IBA 10/2017 - 01/2002
3	Dexmedetomidine FDA Link 01/2002 - 06/2000
2	Streptozocin (Streptozotocin)FDA Link 12/2019 - 02/2001
2	5-HT1A Serotonin ReceptorIBA 01/2018 - 04/2015
2	AntioxidantsIBA 01/2018 - 02/2001
2	salicylhydroxamic acid (SHAM)IBA 01/2018 - 01/2002
2	AnkyrinsIBA 08/2016 - 06/2013
2	TRPA1 Cation ChannelIBA 08/2016 - 06/2013
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 04/2015 - 06/2010
2	Pharmaceutical PreparationsIBA 06/2013 - 05/2001
2	CarrageenanIBA 12/2010 - 01/2002
2	phenylalanyl- leucyl- phenylalanyl- glutaminyl- prolyl- glutaminyl- arginyl- phenylalaninamideIBA 01/2005 - 05/2001
2	AmidesIBA 05/2001 - 01/2001
1	Pregabalin (Lyrica)FDA Link 12/2019
1	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 12/2019
1	Ion Channels (Ion Channel)IBA 01/2018
1	Neurotransmitter Agents (Neurotransmitter)IBA 10/2017
1	Pyruvaldehyde (Methylglyoxal)IBA 08/2016
1	TunicamycinIBA 08/2016
1	Metabotropic Glutamate 5 ReceptorIBA 01/2016
1	Glutamic Acid (Glutamate)FDA Link 04/2015
1	5-HT3 Serotonin Receptors (5 HT3 Receptor)IBA 04/2015
1	N- (2- (4- (2- methoxyphenyl)- 1- piperazinyl)ethyl)- N- (2- pyridinyl)cyclohexanecarboxamideIBA 04/2015
1	8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)IBA 04/2015
1	Ondansetron (Zofran)FDA LinkGeneric 04/2015
1	Serotonin 5-HT1 Receptor AgonistsIBA 04/2015
1	Dizocilpine Maleate (Dizocilpine)IBA 04/2015
1	Sucrose (Saccharose)IBA 05/2014
1	Amitriptyline (Elavil)FDA LinkGeneric 05/2014
1	Antidepressive Agents (Antidepressants)IBA 05/2014
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 12/2013
1	Dynorphins (Dynorphin)IBA 06/2013
1	ProstaglandinsIBA 06/2013
1	Cholecystokinin (Pancreozymin)IBA 06/2013
1	Minocycline (Cyclops)FDA LinkGeneric 06/2013
1	CarbenoxoloneIBA 06/2013
1	A 967079IBA 06/2013
1	cinnamaldehyde (cinnamic aldehyde)FDA Link 06/2013
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 07/2012
1	Fragile X Mental Retardation ProteinIBA 07/2012
1	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 12/2010
1	Memantine (Namenda)FDA Link 06/2010
1	Peptides (Polypeptides)IBA 01/2005
1	Protein Sorting Signals (Signal Peptide)IBA 01/2005
1	neuropeptide FF receptorIBA 01/2005
1	arginylphenylalaninamideIBA 01/2005
1	Oxidopamine (6 Hydroxydopamine)IBA 01/2002
1	Opioid Receptors (Opioid Receptor)IBA 01/2002
1	mu Opioid Receptors (mu Opioid Receptor)IBA 01/2002
1	Naloxone (Narcan)FDA LinkGeneric 05/2001
1	tyrosyl- leucyl- N- methylphenylalanyl- glutaminyl- prolyl- glutaminyl- arginyl- phenylalaninamideIBA 05/2001
1	TurpentineIBA 03/2001
1	nitecapone (OR 462)IBA 02/2001
1	Clonidine (ST 155)FDA LinkGeneric 06/2000
1	Adrenergic Receptors (Adrenergic Receptor)IBA 06/2000
1	Yohimbine (Yocon)IBA 06/2000

Therapy/Procedure

4	Therapeutics 10/2000 - 04/2000
2	Spinal Cord Stimulation 12/2013 - 09/2013
2	Ligation 01/2002 - 05/2001
1	Transcranial Magnetic Stimulation 10/2017
1	Analgesia 12/2010
1	Chemical Sympathectomy 01/2002